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Takeda Reports High Profits But Forecasts Future Slump

9 May 08

Despite reporting its highest-ever net income of ¥355.5 billion (US$3.45 billion), the implications of Takeda's recent US$8.8-billion acquisition of U.S. biotech Millennium Pharmaceuticals have overshadowed its FY 2007/08 annual results, with the company forecasting a 55% drop in profits in FY 2008/09.

Global Insight Perspective

 

Significance

Although Takeda has reported its highest ever full-year net income of ¥355.5 billion (US$3.45 billion), the company failed deliver on its key forecasts from February.

Implications

During the fourth quarter of FY 2007/08, Takeda incurred higher-than-expected costs, notably through a deal to acquire clinical candidates from U.S. biotech Amgen, and the company's R&D expenditure has soared.

Outlook

For the future, Takeda will be weighed down heavily by its US$8.8 billion acquisition of Millennium Pharmaceuticals, which has led to the company forecasting a big slump in its FY 2008/09 profits.

Looking at its other headline figures, Takeda's net sales were up 5.3% to ¥1.375 trillion in FY 2007/08, while its operating income fell by -7.7% to ¥423.1 billion. All of these key indicators were down on its forecasts published in February, at which time it was expecting net sales of ¥1.4 trillion, an operating income of ¥485 billion, and a net income of ¥395 billion. The company's operating income was hit in particular by costs associated with acquiring to the rights to clinical candidates from Amgen (U.S.) in a number of therapeutic areas. This was also reflected in the fact that Takeda's R&D expenditure soared by 42.7% to ¥275.8 billion, which corresponded to 20.1% of its net sales.

Turning to individual divisions, Takeda's pharmaceutical sales grew by 5.8% to ¥1.272 trillion, of which ¥529.7 billion (+2.9%) was derived from its domestic ethical drugs and ¥680.6 billion (+8.2%) from its overseas ethical drugs. The subdued growth rate in the domestic market could be partly attributed to generics-friendly policies that have been implemented by the Japanese government.

Takeda: Selected Results, FY 2007/08

 

¥ bil.

% Change Y/Y

Net Sales

1,374.8

5.3

Pharmaceuticals

1,272.1

5.8

Domestic Ethical Drugs

529.7

2.9

Overseas Ethical Drugs

680.6

8.2

Cost of Sales

278.6

0

Sales, General, and Administrative (SGA) Expenses

673.0

18.7

R&D Expenditure

275.8

42.7

R&D as % of Sales

20.1

N/A

Operating Income

423.1

-7.7

Operating Margin (%) *

30.8

N/A

Net Income

355.5

5.9

Source: Takeda, Global Insight
* Based on Global Insight calculations

Nevertheless, sales of key drugs in Japan continued to increase, notably Blopress (+6.1%), Takepron (+11.8%) and Actos (+23.6%). Actos also performed particularly well in the U.S. market, where its sales were up 17.7% to US$2,786 million—helped of course by the adverse publicity suffered by GlaxoSmithKline's (GSK; U.K.) Avandia.

Takeda: Domestic Sales, FY 2007/08

 

¥ bil.

% Change Y/Y

Blopress

137.1

6.1

Leuplin

66.4

3.3

Takepron

64.8

11.8

Basen

52.8

-5.2

Actos

41.6

23.6

Enbrel

18.8

65.3

Benet

16.5

1.9

Isovorin

12.5

-10.5

Seltouch

12.3

-2.9

Glovenin

8.8

2.3

Pansporin

8.4

-22.9

Dasen

7.7

-5.2

Rheumatrex

7.7

11.6

Firstcin

6.4

-7.5

Leucovorin tablet 25

5.3

-20.8

Source: Takeda

Outlook and Implications

Looking towards FY 2008/09, although Takeda is forecasting strong growth in terms of net sales (+14.2% to ¥1,570 billion), the outlook is less rosy for its other key indicators. The company is forecasting its operating income to plummet by 43.3% to ¥240 billion, with its net income to crash by 55% to ¥160 billion. These steep declines are largely attributable to costs associated with the company's recent US$8.8-billion acquisition of Millennium Pharmaceuticals (see Japan: 10 April 2008: Takeda Opens War Chest with US$8.8-bil. Millennium Acquisition).

Although the acquisition provides a massive boost to the company's drug development ambitions—notably in the field of oncology—the jury is still out as to whether the price tag was too high.

Takeda will face a further financial burden through a recent agreement to purchase Amgen's Japanese subsidiary, while the company has also agreed to pay Abbott (U.S.) US$1.5 billion over five years on revenues from the blockbuster acid reflux drug Prevacid (lanzoprazole; see Japan: 20 March 2008: Abbott Confirms Dissolution of TAP).
 
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